Spectrophotometric Methods for Estimation of Diclofenac Sodium in Tablets
نویسنده
چکیده
Diclofenac sodium or Sodium-2-[(2, 6-dichlorophenyl) amino] phenyl] acetate, is widely used as non-steroidal antiinflammatory agent in therapeutics, it inhibits the cyclooxygenase enzyme1. Various spectrophotometric2-11, chromatographic12-18, colorimetric19-20 and flourimetric21-23 methods have been developed for quantification of diclofenac sodium. Extensive literature survey revealed that a very few UV method is however reported for the estimation of diclofenac sodium in tablet dosage form. Available UV-Visible spectroscopic method are accurate, precise and reproducible, but has used either costly or unstable solvents. That’s why it was thought to develop new simple, economical, accurate, reproducible and rapid analytical methods for estimation of diclofenac sodium in tablets by UV spectroscopy.
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